Acute and chronicpainhas affected humans since the beginning of time. Ancient healers, shamans and, nowadays, medical doctors, naturopaths, chiropractors, and acupuncturists utilize varied approaches to treat both acute and chronic pain syndromes. Chronic pain is diagnosed when a person endures pain in a specific area for more than six weeks—it usually results frominflammation, which creates an imbalance within the body.
Frequently, the following conditions are associated with chronic pain and reduced enjoyment of life:
Osteoarthritisand degenerativejointdiseaseRheumatoid arthritisBack painand degenerative disc diseaseFibromyalgiaPeripheral neuropathyComplex Regional Pain Syndrome (CRPS)Migraine headachesChronicpainrelated to shingles (post-herpetic neuralgia)
Osteoarthritisand degenerativejointdisease
Rheumatoid arthritis
Back painand degenerative disc disease
Fibromyalgia
Peripheral neuropathy
Complex Regional Pain Syndrome (CRPS)
Migraine headaches
Chronicpainrelated to shingles (post-herpetic neuralgia)
Drug companies have created medications to help patients reduce the pain associated with these conditions and improve quality of life. However, medications are not without side effects, some of which can be life-threatening. I frequently prescribe these medications as they work very well. However, I believe they should be used as a last resort—getting to the root cause of theinflammationandpainis a wiser route for long-term management.
The following have been shown to increase pain throughout the body:
SystemicInflammationPoorsleepAltered biomechanics (trouble walking, moving, etc.)Sedentary lifestyleObesityInsulin resistance (due to being overweight and/or obesity)Diet high in animal-based productsDiet high in fast foods and processed foodsRelationship difficulties – A 2014 study in theJournal of Painand a 2017 study in theEuropean Journal of Neuroscienceshowed that negative remarks from another person, i.e. spouse or friend, can worsen your physical painFeelings of guiltFeelings of anger towards another
SystemicInflammation
Poorsleep
Altered biomechanics (trouble walking, moving, etc.)
Sedentary lifestyle
Obesity
Insulin resistance (due to being overweight and/or obesity)
Diet high in animal-based products
Diet high in fast foods and processed foods
Relationship difficulties – A 2014 study in theJournal of Painand a 2017 study in theEuropean Journal of Neuroscienceshowed that negative remarks from another person, i.e. spouse or friend, can worsen your physical pain
Feelings of guilt
Feelings of anger towards another
Addressing the underlying problem causing chronicpainis the first step that should be undertaken. However, sometimes medications may be needed, especially when lifestyle and supplements are not sufficient. Do not stop taking any medications without consulting your physician first.
The following can help reduce chronic pain symptoms:
Routine exercise as toleratedGoodsleephabitsStressreliefImprovingblood sugarcontrol in those with diabetesConsuming a primarily plant-based dietConsuming a diet rich innuts, seeds, and foods withomega-3 fats.Love of self and othersAttitude of forgiveness toward self and othersGood social supportCertain medications and supplements
Routine exercise as tolerated
Goodsleephabits
Stressrelief
Improvingblood sugarcontrol in those with diabetes
Consuming a primarily plant-based diet
Consuming a diet rich innuts, seeds, and foods withomega-3 fats.
Love of self and others
Attitude of forgiveness toward self and others
Good social support
Certain medications and supplements
The Good and Bad of Prescription Pain Medications
Common medications used for chronic pain include acetaminophen (Tylenol, paracetamol), Non-Steroidal Anti-inflammatory Drugs (NSAIDS), and narcotic-based medicinals. These classes of medications have helped millions get through the day by reducing pain. But, there are risks, which will be discussed below.
Paracetamol, or acetaminophen in the United States, is also known by the trade names of Tylenol, Calpol or Panadol. Discovered in 1877, this medication is available without a prescription. While helpful for many, paracetamol can put oxidative stress on theliver. When taken in excess or for prolonged periods of time, it can induce liver damage or, rarely, fatal skin reactions where the skin severely blisters. Avoid drinking alcohol if you consume paracetamol or acetaminophen regularly.
Nutrients depleted:
Glutathione
Glutathione
Supplements advised:
NAC or N-acetyl cysteine(the body converts NAC to glutathione)
NAC or N-acetyl cysteine(the body converts NAC to glutathione)
Non-Steroidal Anti-Inflammatory (NSAIDs) drugs are available with and without a doctor’s prescription, depending on their strength. This category of medications is frequently used to treat headaches, back aches, neck pain, and arthritis-related pain.
I frequently prescribe them, when appropriate. When taken for a few days or weeks, they are relatively safe. However, these medications are not without side effects when used long-term for chronic pain and can increases risk of stomachulcer,kidneydisease, stroke, andheartattacks.
In 1999, the Federal Drug Administration approved rofecoxib (Vioxx, Ceoxx, and Ceeoxx) for treatment ofosteoarthritispain. Five years later, the medication was withdrawn from the market after it was blamed for causing heart attacks.
Experts believe up to 60,000 people may have died due to side effects of this drug. Fortunately, the other options on the market appear to be safer, but they do have risks associated with them, including nutrient depletion.
Drugs in this class include: Ibuprofen (Advil, Motrin, Brufen, Nurofen, Eve, etc.), Naproxen (Naprosyn, Aleve), diclofenac,indomethacin and meloxicam (Mobic)
Nutrients Depleted
Folate – important for heart and brain healthVitamin C – may account for some of the increased bruising seen in chronic usersVitamin E – important for heart healthMelatonin – may account for insomnia related symptoms some experience
Folate – important for heart and brain health
Vitamin C – may account for some of the increased bruising seen in chronic users
Vitamin E – important for heart health
Melatonin – may account for insomnia related symptoms some experience
Supplements Advised
Folate– take as directed on the labelVitamin C– 500 to 2,000 mg per dayVitamin E– 200 to 400 IU per dayMelatonin– 3 mg to 10 mg 1-2 hours before bed
Folate– take as directed on the label
Vitamin C– 500 to 2,000 mg per day
Vitamin E– 200 to 400 IU per day
Melatonin– 3 mg to 10 mg 1-2 hours before bed
Narcotics are commonly used for chronicpaindisorders. They are derived from the opium poppy. They do not fix the underlying problem nor reduce inflammation—they simply create a sense of euphoria or well being. Overuse and abuse of narcotics is an epidemic in the United States, Europe, Russia and Asia. When used short term, they can be helpful. Long-term use may actually increase pain levels and increase the risk for a person to stop breathing. According to the Centers for Disease Control (CDC), in 2015, more than 33,000 people died from an opiate overdose in the United States. Half the deaths were due to prescription opiate drugs. One in ten people who take these medications is at risk for addiction.
Drugs in this class include: Codeine, tramadol, hydrocodone, oxycodone, morphine sulfate, fentanyl (see acetaminophen /paracetamol if taking combination narcotic/acetaminophen/APAP).
Cigarette use makes narcotics less effective by increasing body’s elimination of the narcotic. When narcotics are combined with alcohol or other controlled medications, the results can be fatal—the combination can result in heart rate to slow and breathing stop.
Nutrients Depleted
Vitamin CMelatonin
Vitamin C
Melatonin
Supplements Advised:
Vitamin C– 500 to 2,000 mg per dayMelatonin– 3 mg to 10 mg 1-2 hours before bed
Vitamin C– 500 to 2,000 mg per day
Melatonin– 3 mg to 10 mg 1-2 hours before bed
Safer Alternatives Using Nutrition and Natural Anti-inflammatory Supplements
Consuming a primarily plant-based diet is the best for reducing chronicinflammationandpainin thejointsandback.Studies demonstrate that the Mediterranean diet can be helpful in reducing joint-related pain fromarthritis. This diet is rich in fruits, vegetables, fish, poultry andolive oil.A study in theLancetdemonstrated that patients who consumed avegan,gluten-freediet for three to five months and then switched to a lacto-vegetarian (dairy-vegetarian) diet significantly reduced their joint pain for up to 1 year.Limiting animal-based products such as dairy, cheese, beef, and chicken helps reduce chronic pain.Grass fed, hormone and antibiotic-free beef, and poultry are a better option.Avoid sugars, simple carbohydrates. trans-fats (hydrogenated oils) which cause more inflammation and, therefore, more pain.Consume cultured foods in your diet such askefir,kombucha,misosoup, andsauerkrautReach your optimal weight, which for most is a body mass index (BMI) < 25. Carrying excess weight, especially in the abdomen, places more stress on your back and joints. Extra weight also increases inflammatory proteins (ie. cytokines) in your blood resulting in more elevated pain.Organic fruits and vegetables contain phytonutrients, which decrease inflammation and help reduce overall pain. Aim for five to nine servings per day. Familiarize yourself with the Environmental Working Group’s Clean 15 and the Dirty Dozen.People with food sensitivities may have increased joint pain with dairy, grains (gluten sensitivity), and nightshade vegetables (tobacco, tomato, white potato, and bell peppers).Do a two-week elimination diet to see if these foods are associated with your joint pain.
Consuming a primarily plant-based diet is the best for reducing chronicinflammationandpainin thejointsandback.
Studies demonstrate that the Mediterranean diet can be helpful in reducing joint-related pain fromarthritis. This diet is rich in fruits, vegetables, fish, poultry andolive oil.
A study in theLancetdemonstrated that patients who consumed avegan,gluten-freediet for three to five months and then switched to a lacto-vegetarian (dairy-vegetarian) diet significantly reduced their joint pain for up to 1 year.
Limiting animal-based products such as dairy, cheese, beef, and chicken helps reduce chronic pain.Grass fed, hormone and antibiotic-free beef, and poultry are a better option.
Avoid sugars, simple carbohydrates. trans-fats (hydrogenated oils) which cause more inflammation and, therefore, more pain.
Consume cultured foods in your diet such askefir,kombucha,misosoup, andsauerkraut
Reach your optimal weight, which for most is a body mass index (BMI) < 25. Carrying excess weight, especially in the abdomen, places more stress on your back and joints. Extra weight also increases inflammatory proteins (ie. cytokines) in your blood resulting in more elevated pain.
Organic fruits and vegetables contain phytonutrients, which decrease inflammation and help reduce overall pain. Aim for five to nine servings per day. Familiarize yourself with the Environmental Working Group’s Clean 15 and the Dirty Dozen.
People with food sensitivities may have increased joint pain with dairy, grains (gluten sensitivity), and nightshade vegetables (tobacco, tomato, white potato, and bell peppers).
Do a two-week elimination diet to see if these foods are associated with your joint pain.
Acupuncture and Qigong may help with kneearthritispain.Mindfulness and meditation is helpful in minimizing pain associated withosteoarthritisand rheumatoid arthritis.Tai Chi has been shown to be helpful in alleviating knee pain among other pains.Yoga has been shown to lessen joint pain in those with rheumatoid and osteoarthritis.
Acupuncture and Qigong may help with kneearthritispain.
Mindfulness and meditation is helpful in minimizing pain associated withosteoarthritisand rheumatoid arthritis.
Tai Chi has been shown to be helpful in alleviating knee pain among other pains.
Yoga has been shown to lessen joint pain in those with rheumatoid and osteoarthritis.
Primary Nutritional Supplements for Chronic Inflammation and Pain
Curcumin/Turmeric- Studies show this herb is helpful in reducing pain in both rheumatoid and osteoarthritis. It can also be helpful in those with back pain and nerve- related pain. Scientists have discovered that this herbdoes things similar to multiple blockbuster prescription drugs since it modifies NF-KB signaling and reduces pro-inflammatory chemicals such as COX-2 and 5-LOX.Suggested dose: 500 mg one up to three times per dayOmega 3 Fish Oil (EPA/DHA)- Studies show essential fatty acids help improve pain and reduce use of NSAIDs. Studies also show a reduction of joint stiffness when fish oil is taken daily. Omega-3s can also be helpful for those with chronic back pain.Suggested dose: 500 mg up to 4,000 mg per day
Curcumin/Turmeric- Studies show this herb is helpful in reducing pain in both rheumatoid and osteoarthritis. It can also be helpful in those with back pain and nerve- related pain. Scientists have discovered that this herbdoes things similar to multiple blockbuster prescription drugs since it modifies NF-KB signaling and reduces pro-inflammatory chemicals such as COX-2 and 5-LOX.Suggested dose: 500 mg one up to three times per day
Omega 3 Fish Oil (EPA/DHA)- Studies show essential fatty acids help improve pain and reduce use of NSAIDs. Studies also show a reduction of joint stiffness when fish oil is taken daily. Omega-3s can also be helpful for those with chronic back pain.Suggested dose: 500 mg up to 4,000 mg per day
Nigella Sativa (Black cumin seed oil)- A medicinal herb shown to reduce inflammation in both rheumatoid arthritisand osteoarthritis.It does so by inhibiting inflammatory chemicals called interleukin-1, 6 and nuclear factorKB. Suggested dose: As directed on the labelBoswellia- This Ayurvedic herbal supplement can help reduce pain and inflammation markers in the blood, like CRP in rheumatoid arthritis, and reduce pain due to osteoarthritis.Studies also show boswellia can be helpful in those with pain due to peripheral neuropathy. Suggested dose: 50 mg per day or as directed.Ginger- Ginger can help reduce inflammatory markers and pain in arthritis. Ginger is a COX inhibitor, meaning it works similarly to ibuprofen and naproxen to reduce pain and inflammation. Fortunately, it does not have the dangerous side effects. Suggested dose: 25 mg daily or as directed
Nigella Sativa (Black cumin seed oil)- A medicinal herb shown to reduce inflammation in both rheumatoid arthritisand osteoarthritis.It does so by inhibiting inflammatory chemicals called interleukin-1, 6 and nuclear factorKB. Suggested dose: As directed on the label
Boswellia- This Ayurvedic herbal supplement can help reduce pain and inflammation markers in the blood, like CRP in rheumatoid arthritis, and reduce pain due to osteoarthritis.Studies also show boswellia can be helpful in those with pain due to peripheral neuropathy. Suggested dose: 50 mg per day or as directed.
Ginger- Ginger can help reduce inflammatory markers and pain in arthritis. Ginger is a COX inhibitor, meaning it works similarly to ibuprofen and naproxen to reduce pain and inflammation. Fortunately, it does not have the dangerous side effects. Suggested dose: 25 mg daily or as directed
The above supplements can be taken separately or taken in acombination nutraceutical supplement.
Vitamin D–Studies show that those with higher levels of vitamin D are less likely to develop rheumatoid arthritis. Routine consumption also reduces chronic pain. Suggested dose: 2,000- 5,000 IU daily.Probiotics–Probiotics, can help reduce chronic pain by optimizing gut health and helping to reverse aleaky gut. Consumption of a probiotic that contains bothLactobacillusandBifidobacteriumis advised. Suggested dose: 5 billion to 30 billion units once or twice per dayMagnesium– Studies show magnesium, a natural muscle relaxer, can be helpful in those with fibromyalgia. A 2013 study inRheumatology Internationalshowed that oral magnesium citrate reduced pain in those with fibromyalgia-related pain. Further, a 2015 study in theJournal of Integrative Medicinedemonstrated that when magnesium chloride was applied to the skin, there was a reduction in pain. Some studies have also shown that a combination of magnesium and malic acid could be helpful. Magnesium is available in capsules, sprays, and lotion formulations. Suggested oral dose: 125 mg to 500 mg or as directed on label
Vitamin D–Studies show that those with higher levels of vitamin D are less likely to develop rheumatoid arthritis. Routine consumption also reduces chronic pain. Suggested dose: 2,000- 5,000 IU daily.
Probiotics–Probiotics, can help reduce chronic pain by optimizing gut health and helping to reverse aleaky gut. Consumption of a probiotic that contains bothLactobacillusandBifidobacteriumis advised. Suggested dose: 5 billion to 30 billion units once or twice per day
Magnesium– Studies show magnesium, a natural muscle relaxer, can be helpful in those with fibromyalgia. A 2013 study inRheumatology Internationalshowed that oral magnesium citrate reduced pain in those with fibromyalgia-related pain. Further, a 2015 study in theJournal of Integrative Medicinedemonstrated that when magnesium chloride was applied to the skin, there was a reduction in pain. Some studies have also shown that a combination of magnesium and malic acid could be helpful. Magnesium is available in capsules, sprays, and lotion formulations. Suggested oral dose: 125 mg to 500 mg or as directed on label
Secondary Nutritional Supplements for Chronic Pain
Glucosamine-Chondroitin Sulfatehas been shown to reduce knee pain, according to a large review that compared 4,900 patients who took the supplement vs 4,100 who took a placebo.SAM-eis also effective in lowering pain associated with chronic arthritis and neuropathy pain. Suggested dose: 400 mg 2-3 times per dayBromelainis an enzyme extracted from pineapples. It helps reduce chronic pain in the joints due to inflammation. Bromelain could also help pain associated with peripheral diabetic neuropathy. Suggested dose: Bromelain 500 mg 2-3 times per dayWhite Willow Barkhas been used by Native Americans for fever and pain for centuries. It contains salicin, the compound aspirin comes from. Do not take this herb if you take aspirin, blood thinners or NSAIDs drugs. Suggested dose: Take as directed on the label
Glucosamine-Chondroitin Sulfatehas been shown to reduce knee pain, according to a large review that compared 4,900 patients who took the supplement vs 4,100 who took a placebo.
SAM-eis also effective in lowering pain associated with chronic arthritis and neuropathy pain. Suggested dose: 400 mg 2-3 times per day
Bromelainis an enzyme extracted from pineapples. It helps reduce chronic pain in the joints due to inflammation. Bromelain could also help pain associated with peripheral diabetic neuropathy. Suggested dose: Bromelain 500 mg 2-3 times per day
White Willow Barkhas been used by Native Americans for fever and pain for centuries. It contains salicin, the compound aspirin comes from. Do not take this herb if you take aspirin, blood thinners or NSAIDs drugs. Suggested dose: Take as directed on the label
Note:If you are on blood thinners or other prescription medications, ask your healthcare provider before starting any supplement for acute or chronicpain.
Summary
Chronicpainis a primary cause of life dissatisfaction. Prescription medications can be helpful but are not without side effects which concern many. Balancing risks and benefits is crucial. Choosing a healthy lifestyle that focuses on generous daily servings of fruits, vegetables and increased physical activity as tolerated is instrumental to feeling better and reducing chronic inflammation. There are various supplements on the market which have been helpful for many people who are afflicted with chronic pain. Many start with supplements such asvitamin D,Omega-3 fish oilandprobiotics. Thereafter, many consider addingmagnesium,turmeric,gingerand others as discussed above. Go forth and seek wellness and happiness. Eat healthy, think healthy, and be healthy.